Total Laryngectomy

I. GENERAL CONSIDERATIONS

A. Indications

1. Oncologic

a. T4 glottic, supraglottic, or subglottic carcinoma

b. T3 glottic or subglottic carcinoma, some T3 supraglottic carcinomas (with extension to cause cord fixation)

c. Glottic or supraglottic carcinoma involving the posterior commissure

d. Irradiation failures not amenable to conservation laryngeal procedures

e. May be considered in patients with large tumors of the base of tongue or supraglottis in whom aspiration is a concern

f. Extended partial laryngectomy, “near-total laryngectomy,” irradiation with surgical salvage, and protocols involving chemotherapy with or without surgery are alternatives to total laryngectomy as an initial treatment approach

2. Chronic aspiration from glottic incompetence not amenable to conservative treatment

3. Chondroradionecrosis of the larynx

II. PREOPERATIVE CONSIDERATIONS

A. Evaluation
1. CT of larynx and neck

2. Panendoscopy and biopsies

3. Consult to radiation oncology

B. Counseling

1. Speech pathology consultation preoperatively. Should include description of voice restoration procedures and demonstration of educational videos (such as Life Without the Larynx).

2. Counseling about avoiding situations where drowning is a possibility (ie, fishing, swimming).

C. Consent for Surgery

1. Describe procedure: “Removal of voice box resulting in a hole in the neck, which is necessary for breathing purposes (with or without neck dissection).” Usually include potential for pectoralis major myocutaneous flap (PMC) in the event the tumor extent is found to be greater than initially determined.

2. Describe potential complications

a. Bleeding

b. Infection

c. Anesthesia-related complications

d. Damage to adjacent structures

e. Salivary fistula

f. Stomal stenosis

g. Swallowing difficulties

III. NURSING CONSIDERATIONS

A. Room Setup
See Basic Soft Tissue Room Setup

B. Instrumentation and Equipment

1. Standard
a. Major instrument tray #1, Otolaryngology

b. Major instrument tray #2, Otolaryngology

c. Bipolar forceps tray

2. Special

a. Tracheotomy tray

b. Varidyne vacuum controller

c. Sterile anesthetic breathing circuit and tubing

d. Rousch Laryngoflex 7 mm endotracheal tube

e. Corpak feeding tube

C. Medications (specific to nursing)

Antibiotic ointment

D. Prep and Drape

1. Standard prep, 10% providone iodine

2. Drape

a. Head drape

b. Towels from nose to umbilicus (for possible PMC flap) and shoulder to shoulder; drape endotracheal tube into surgical field

c. Split sheet

E. Drains and Dressings

Varidyne vacuum suction: 7 mm or 10 mm x 3 mm

F. Special Considerations

1. If Tracheotomy is done as a separate procedure, a separate setup will be necessary

2. Panendoscopy and/or radical neck dissection may be done in conjunction with procedure

3. Need for flexible endotracheal tube and sterile anesthetic tubing to replace oral endotracheal intubation at time of tracheostomal maturation

IV. ANESTHESIA CONSIDERATIONS

A. General

Preferable to use oral endotracheal anesthesia with conversion to anesthetic through tracheostoma via flexible endotracheal tube early in procedure rather than perform tracheotomy as separate early procedure

B. Specific

1. Occasionally will need to do local tracheotomy initially due to airway compromise or difficulty with intubation

2. Need for sterile anesthetic tubing

3. May be beneficial to have patient breathing spontaneously at end of procedure so as to preclude the need for a tracheotomy tube in fresh stoma

V. OPERATIVE PROCEDURE

A. Table is turned 180° (Mayfield headrest helpful in selected cases, not routinely).

B. Shoulder roll is needed.

C. Incision

1. Skin incision may be made with electrocautery (on blend of 20/20 cut/coag) from inferior to mastoid tip, similar location on opposite side if bilateral neck dissections to be done; may make “apron flap” smaller if full radical or comprehensive neck dissections not required.

2. Lower border of incision will be upper aspect of tracheostoma (about 2 to 4 cm above sternal notch).

3. Alternatively tracheostoma may come out of lower flap separate from apron incision. Should leave adequate distance between these incisions to retain an adequate blood supply to the intervening skin.

D. Flap elevation should be in the subplatysmal plane, immediately above anterior and external jugular veins.

E. Transect strap muscles inferiorly (hemostat dissection/monopolar cautery on cutting).

F. Divide thyroid isthmus, oversew and dissect thyroid gland away from the trachea (may remove ipsilateral lobe along with larynx).

G. Trim 2 to 4 cm in half-moon shape from inferior skin flap and remove subcutaneous fat in preparation for maturing lower border of tracheostoma. With 3-0 vicryl, suture anterior tracheal wall in 3 to 5 sites to under surface of inferior flap to begin formation of a mature tracheostoma.

H. Clean soft tissue off anterior tracheal wall and incise between second and third rings (lower if concern for subglottic extension exists).

1. Continue incision superolaterally to bevel lateral tracheal walls superiorly to enlarge tracheostoma.

2. One method to remove the endotracheal tube without requiring anesthetist to come to head of table to withdraw tube: After puncturing balloon of endotracheal tube, in a “hand-over-hand fashion” with 2 large hemostats, pull tip of tube out of tracheotomy. Advance the tube inferiorly through the glottis and cut with heavy scissors, allowing the upper two-thirds remnant to retract superiorly, still attached to tape at the mouth.

3. Inspect subglottis from below to ensure adequate margin has been obtained.

4. Place new flexible endotracheal tube into the trachea and secure to anterior tracheal wall or chest with suture, attach to sterile anesthesia tubing, and resume ventilation through the neck.

I. Be prepared to perform a radical or modified radical neck dissection if previously unrecognized neck disease becomes apparent after flap elevation (see Cervical Lymphadenectomy: General Considerations)

1. Bilateral Levels II, III, and IV neck dissections are commonly employed for cN0 neck disease.

2. If irradiation is clearly indicated postoperatively as an adjunct to laryngectomy (based on tumor characteristics as the primary site), elective neck dissection (for cN0 necks) is not necessary.

3. Comprehensive radical or modified radical neck dissection is done for clinically N-positive disease.

J. Isolate the inferior pedicle of ipsilateral thyroid lobe and ligate vessels.

1. Good practice but not essential to identify and preserve pedicled inferior parathyroid

2. Also good practice but even less essential to identify the recurrent laryngeal nerve prior to its transection

K. Detach constrictor muscles from the thyroid ala with cautery or scalpel blade. The mucosa of the pyriform sinus on uninvolved side may be mobilized medially with a sponge, Kitner, or Freer elevator.

L. Dissect suprahyoid musculature off of superior border of hyoid bone with monopolar dissection staying in the midline well away from the hypoglossal nerves. Grasp the midline of the hyoid with an Allis clamp.

1. Heavy Mayo scissors dissection laterally to isolate greater cornu of hyoid bilaterally

2. Hug corner of greater cornu to avoid hypoglossal nerve; if neck dissection done, the hypoglossal nerves will be under direct vision

M. Entry into the larynx from above

1. Should enter larynx as far from tumor as possible: choices include the vallecula or pyriform sinus on side opposite tumor or from below; most commonly enter from the vallecula.

2. With finger palpation of vallecula, insert Army-Navy retractor through the mouth with end of retractor now palpable through the neck immediately above hyoid.

3. This maneuver keeps the surgeon out of the pre-epiglottic space.

4. Cut with cautery down to the Army-Navy retractor that will now appear into the neck wound.

5. Dissect laterally from point of entry to expose supraglottis.

6. May place Allis clamp on epiglottis for retraction to help gain full visualization of tumor.

N. Heavy scissors cuts (Mayo or Metzenbaum) may be made on less involved side along lateral pharyngeal wall to “open pharynx like a book.”

1. On less involved side, cuts may be made to hug arytenoids and cricoid to preserve pyriform sinus mucosa.

2. Superior laryngeal neurovascular pedicle will be encountered with these cuts and should be ligated.

O. With the excellent exposure now available, the involved side of the larynx is separated from posterolateral wall mucosa also with scissors cuts. This allows good visualization to obtain adequate margins.

P. Final separation of the larynx is performed from below with scalpel incision of posterior tracheal wall to identify the gray line (avascular plane between esophagus and trachea).

Larynx removed from patient with upward traction on the larynx permitting inspection of surgical margin, esophageal introitus, and trachea as final cuts are made.

Q. Pharyngeal Closure

1. Place NG Corpak feeding tube before closure.

2. T-shaped closure with 3-0 vicryl or 4-0 vicryl in running modified Connell or true Connell technique for first layer

3. Second layer of interrupted 3-0 vicryl to ensure the deeper running layer is imbricated

4. Third layer with interrupted 3-0 vicryl to loosely approximate constrictor muscles (overly tight closure may lead to narrowing with subsequent dysphagia or failure of TEP speech may choose to avoid third layer)

R. Tracheostoma

1. Take bilateral “cookie bites” out of sternal head of sternocleidomastoid (SCM) to allow room for tracheostoma; may tack thyroid remnant laterally under SCM.

2. Remove 2 to 4 cm elliptical segment from upper skin flap above tracheostoma.

3. Suture undersurface of upper and lower flaps (dermis, 2 to 3 mm from skin edge) to cartilage of trachea with 0 or 00 chromic or 3-0 vicryl.

4. Approximate skin of flaps to mucosa of trachea (covering exposed cartilage) with 4-0 chromic.

S. Suction drains (3 or 4)

1. Bilaterally placed active suction drains to both “gutters” (along internal jugular veins)

2. Third drain placed horizontally just above upper aspect of tracheostoma

3. Consider fourth drain across submental area

T. Platysma closed with 3-0 vicryl and the skin is stapled.

VI. POSTOPERATIVE CARE

A. Drains
1. Leave 3 or 4 drains in place a minimum of 3 days.

2. Begin to remove individual drains once output diminishes to 10 cc per 8-hour shift (30 cc per day).

B. Feeding

1. Begin oral feeding on postoperative day 7 in uncomplicated resection in the nonirradiated patient.

2. Begin oral feeding on postoperative day 14 in irradiated patient (rule: delay by 1 additional day per each 1,000 cGy the time to feeding; ie, no irradiation, then postoperative day 7; 7,0000 cGy, then postoperative day 14).

C. Discharge

1. May discharge home the day after last drain is removed and begin feeding as outpatient.

2. It is generally best not to discharge before postoperative day 6 in order to observe for fistula.

D. Be aware of high incidence of hypothyroidism (60%) with total laryngectomy patients who have been irradiated.

VII. CPT CODING

A. 31360, Laryngectomy; total, without radical neck dissection

B. 31365, Laryngectomy; total, with radical neck dissection

VIII. SUGGESTED READING

A. Sheehan AJ, Shaw HJ. Total laryngectomy for squamous carcinoma of the glottis. J Laryngol Otol. 1979;93:461-475.

B. Wang CP, Tseng TC, Lee RC, Chang SY. The techniques of nonmuscular closure of hypopharyngeal defect following total laryngectomy: the assessment of complication and pharyngoesophageal segment. J Laryngol Otol. 1997;111:1060-1063.

C. Wei WI, Lau WF, Lam KH. Entering the pharynx in total laryngectomy. J Laryngol Otol. 1987;101:589-591.